Albumin is made by the liver; globulins include antibodies and other carrier proteins. A low A/G ratio can mean albumin is low (liver disease, malnutrition, kidney loss) or globulins are high (chronic infection, autoimmune disease, myeloma); a high ratio can mean low antibodies.
How to use the Albumin to Globulin Ratio Calculator
- Total protein
- Albumin
Results update as you type, and every field accepts the units shown in its menu.
How it works
Enter total protein and albumin from the same blood test.
Inputs explained
| Field | What to enter |
|---|---|
| Total protein | Units: g/dL, g/L |
| Albumin | Units: g/dL, g/L |
What each result means
- Globulin = [Total protein] – [Albumin]
- A/G ratio = [Albumin]÷([Total protein] – [Albumin])
Example values
How the main result changes when Total protein changes and everything else stays at the example values above:
| Total protein (g/dL) | A/G ratio |
|---|---|
| 3.6 | -7 |
| 5.4 | 3.5 |
| 7.2 | 1.4 |
| 9 | 0.88 |
| 10.8 | 0.64 |
| 14.4 | 0.41 |
Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.
Formula
Globulin = total protein − albumin
A/G ratio = albumin ÷ globulin
Worked example
Inputs — Total protein: 7.2 g/dL; Albumin: 4.2 g/dL.
Results — Globulin = 3 g/dL; A/G ratio = 1.4.
Key terms
- Globulin
- Blood proteins other than albumin.
Frequently asked questions
What is a normal A/G ratio?
About 1.1–2.5.
What does a high globulin mean?
Chronic inflammation, infection, autoimmune disease or a paraprotein such as in myeloma.
What test follows an abnormal ratio?
Serum protein electrophoresis.