# HOMA-IR Calculator (Insulin Resistance)

URL: https://speedycalculator.com/calculators/health/homa-ir/
Last updated: 2026-10-25

> The HOMA-IR calculator estimates insulin resistance from fasting glucose and fasting insulin using the homeostatic model assessment. Higher values suggest greater insulin resistance.

## Inputs

- Fasting glucose (mg/dL, mmol/L)
- Fasting insulin (µU/mL)

## Results

- HOMA-IR
- HOMA-%B (beta-cell function)

## Formula

```
HOMA-IR = fasting glucose (mg/dL) × fasting insulin (µU/mL) ÷ 405
```

## Explanation

HOMA-IR is widely used in research and some clinics to track insulin resistance, though cut-offs vary between populations.

### How to use the HOMA-IR Calculator

- **Fasting glucose**
- **Fasting insulin**

Results update as you type, and every field accepts the units shown in its menu.

### How it works

Multiply fasting glucose by fasting insulin and divide by 405 (or by 22.5 when glucose is in mmol/L).

### Inputs explained

FieldWhat to enterFasting glucoseUnits: mg/dL, mmol/LFasting insulinIn µU/mL

### What each result means

- **HOMA-IR** = [Fasting glucose] × [Fasting insulin] ÷ 405
- **HOMA-%B (beta-cell function)** = 360 × [Fasting insulin] ÷ ([Fasting glucose] - 63)

### Example values

How the main result changes when **Fasting glucose** changes and everything else stays at the example values above:

Fasting glucose (mg/dL)HOMA-IR47.51.1771.251.76952.35118.752.93142.53.521904.69
*Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.*

## Worked example

Inputs — Fasting glucose: 95 mg/dL; Fasting insulin: 10 µU/mL.

Results — **HOMA-IR = 2.35**; HOMA-%B (beta-cell function) = 113 %.

## FAQ

**Is there a universal cut-off?**
No; thresholds from about 1.9 to 2.9 are used depending on the population.

**Do I need to fast?**
Yes, both values must be fasting measurements.

**What formula does the HOMA-IR Calculator use?**
HOMA-IR = fasting glucose (mg/dL) × fasting insulin (µU/mL) ÷ 405.


## Sources

- [Matthews DR et al. Homeostasis model assessment. Diabetologia, 1985](https://pubmed.ncbi.nlm.nih.gov/3899825/)