Lung Nodule Growth Rate Calculator (Volume Doubling Time)

Quick answer

The lung nodule growth calculator estimates the volume doubling time of a pulmonary nodule from its diameter (or volume) on two CT scans and the time between them – a key clue to whether a nodule is benign or malignant.

mm
mm
First volume
113 mm³
Second volume
221 mm³
Volume change
95 %
Volume doubling time
124 days
Suspicious for malignancy

Most lung cancers double in volume within 20–400 days. Very fast growth (under 20 days) suggests infection, while no growth over 2 years for a solid nodule usually indicates a benign lesion. Volumetry is more precise than diameter.

How to use the Lung Nodule Growth Rate Calculator

  1. First diameter
  2. Second diameter
  3. Days between scans

Results update as you type, and every field accepts the units shown in its menu.

How it works

Enter the average nodule diameter on each scan and the days between them.

Inputs explained

Field What to enter
First diameter In mm
Second diameter In mm
Days between scans A number

What each result means

  • First volume = pi÷6×[First diameter]^3
  • Second volume = pi÷6×[Second diameter]^3
  • Volume change = ([Second volume]÷[First volume] – 1)×100

Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.

Formula

Volume = π/6 × diameter³ Volume doubling time (days) = days × ln 2 ÷ ln(V₂ ÷ V₁) < 400 days: suspicious for malignancy · 400–600 indeterminate · > 600 days usually benign

Worked example

Inputs — First diameter: 6 mm; Second diameter: 7.5 mm; Days between scans: 120.
Results — First volume = 113 mm³; Second volume = 221 mm³; Volume change = 95 %; Volume doubling time = 124 days.

Key terms

VDT
Volume doubling time.

Frequently asked questions

What doubling time suggests cancer?

20–400 days for solid nodules.

Why use volume rather than diameter?

A 26% increase in diameter already doubles the volume.

What if the nodule shrinks?

Shrinking nodules are usually inflammatory or infectious.

Sources

  1. MacMahon H et al. Fleischner Society guidelines for incidental pulmonary nodules, 2017. Radiology

Cite this calculator

Speedy Calculator. (2026). Lung Nodule Growth Rate Calculator (Volume Doubling Time). Speedy Calculator. https://speedycalculator.com/calculators/health/lung-nodule-growth-rate/