A large prostate produces more PSA, so PSA alone can mislead. PSA density above 0.15 is associated with a higher chance of clinically significant prostate cancer and is used, with MRI findings, to decide on biopsy.
How to use the PSA Density Calculator
- PSA
- Prostate volume input
- Prostate volume
- Length
- Width
- Height
Results update as you type, and every field accepts the units shown in its menu.
How it works
Enter PSA and the prostate volume from ultrasound or MRI (or its three dimensions).
Inputs explained
| Field | What to enter |
|---|---|
| PSA | In ng/mL |
| Prostate volume input | Choose one: Volume, Three dimensions |
| Prostate volume | In mL |
| Length | Units: cm, in, m, ft, mm |
| Width | Units: cm, in, m, ft, mm |
| Height | Units: cm, in, m, ft, mm |
Example values
How the main result changes when PSA changes and everything else stays at the example values above:
| PSA (ng/mL) | PSA density (ng/mL/cc) |
|---|---|
| 3 | 0.08 |
| 4.5 | 0.11 |
| 6 | 0.15 |
| 7.5 | 0.19 |
| 9 | 0.23 |
| 12 | 0.3 |
Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.
Formula
PSA density = PSA (ng/mL) ÷ prostate volume (mL)
≥ 0.15 ng/mL/cc: higher risk of clinically significant cancer
Worked example
Inputs — PSA: 6 ng/mL; Prostate volume input: Volume; Prostate volume: 40 mL.
Results — Prostate volume = 40 mL; PSA density = 0.15 ng/mL/cc.
Key terms
- PSA
- Prostate-specific antigen.
Frequently asked questions
What is a normal PSA density?
Below 0.15 ng/mL/cc, and below 0.10 is reassuring.
Does a high PSA density mean cancer?
No – it raises the probability; MRI and biopsy are needed to diagnose cancer.
How is prostate volume measured?
By transrectal ultrasound or MRI.