IPI Calculator (DLBCL Prognosis)

Quick answer

The IPI calculator scores the International Prognostic Index for diffuse large B-cell lymphoma – age, stage, LDH, performance status and extranodal sites – and gives the standard and revised (R-IPI) risk groups for patients treated with R-CHOP.

IPI score
2 / 5
IPI risk group
Low-intermediate
Revised IPI (R-CHOP era)
Good (about 79%)

The IPI was published in 1993 and remains the main prognostic tool in aggressive lymphoma. The revised IPI uses the same five factors but regroups them for the rituximab era.

How to use the IPI Calculator

  1. Age over 60
  2. Ann Arbor stage III or IV
  3. Serum LDH above the upper limit of normal
  4. ECOG performance status 2 or more
  5. More than one extranodal site

Results update as you type, and every field accepts the units shown in its menu.

How it works

Each answer carries the points shown in the published score. The calculator adds them up and maps the total to the published interpretation.

Scoring table

Item Answers and points
Age over 60 No = 0; Yes = 1
Ann Arbor stage III or IV No = 0; Yes = 1
Serum LDH above the upper limit of normal No = 0; Yes = 1
ECOG performance status 2 or more No = 0; Yes = 1
More than one extranodal site No = 0; Yes = 1

Inputs explained

Field What to enter
Age over 60 Choose one: No, Yes
Ann Arbor stage III or IV Choose one: No, Yes
Serum LDH above the upper limit of normal Choose one: No, Yes
ECOG performance status 2 or more Choose one: No, Yes
More than one extranodal site Choose one: No, Yes

Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.

Formula

Score = sum of the points for each item

Worked example

Inputs — Age over 60: Yes; Ann Arbor stage III or IV: No; Serum LDH above the upper limit of normal: Yes; ECOG performance status 2 or more: No; More than one extranodal site: No.
Results — IPI score = 2 / 5; IPI risk group = Low-intermediate; Revised IPI (R-CHOP era) = Good (about 79%).

Key terms

DLBCL
Diffuse large B-cell lymphoma.
ECOG
Eastern Cooperative Oncology Group performance status.

Frequently asked questions

What is a good IPI score?

0–1.

What is the NCCN-IPI?

A refined version that weights age and LDH more finely.

Does the IPI guide treatment?

It informs prognosis and clinical trial eligibility rather than standard first-line treatment.

Sources

  1. International Non-Hodgkin's Lymphoma Prognostic Factors Project. A predictive model for aggressive NHL. N Engl J Med, 1993
  2. Sehn LH et al. The revised IPI is a better predictor of outcome than the standard IPI. Blood, 2007

Cite this calculator

Speedy Calculator. (2026). IPI Calculator (DLBCL Prognosis). Speedy Calculator. https://speedycalculator.com/calculators/health/diffuse-large-b-cell-lymphoma-prognosis/