HOMA-IR Calculator (Insulin Resistance)

Quick answer

The HOMA-IR calculator estimates insulin resistance from fasting glucose and fasting insulin using the homeostatic model assessment. Higher values suggest greater insulin resistance.

µU/mL
HOMA-IR
—
HOMA-%B (beta-cell function)
— %

HOMA-IR is widely used in research and some clinics to track insulin resistance, though cut-offs vary between populations.

How to use the HOMA-IR Calculator

  1. Fasting glucose
  2. Fasting insulin

Results update as you type, and every field accepts the units shown in its menu.

How it works

Multiply fasting glucose by fasting insulin and divide by 405 (or by 22.5 when glucose is in mmol/L).

Inputs explained

Field What to enter
Fasting glucose Units: mg/dL, mmol/L
Fasting insulin In µU/mL

What each result means

  • HOMA-IR = [Fasting glucose] × [Fasting insulin] ÷ 405
  • HOMA-%B (beta-cell function) = 360 × [Fasting insulin] ÷ ([Fasting glucose] – 63)

Example values

How the main result changes when Fasting glucose changes and everything else stays at the example values above:

Fasting glucose (mg/dL) HOMA-IR
47.5 1.17
71.25 1.76
95 2.35
118.75 2.93
142.5 3.52
190 4.69

Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.

Formula

HOMA-IR = fasting glucose (mg/dL) × fasting insulin (µU/mL) ÷ 405

Worked example

Inputs — Fasting glucose: 95 mg/dL; Fasting insulin: 10 µU/mL.
Results — HOMA-IR = 2.35; HOMA-%B (beta-cell function) = 113 %.

Frequently asked questions

Is there a universal cut-off?

No; thresholds from about 1.9 to 2.9 are used depending on the population.

Do I need to fast?

Yes, both values must be fasting measurements.

What formula does the HOMA-IR Calculator use?

HOMA-IR = fasting glucose (mg/dL) × fasting insulin (µU/mL) ÷ 405.

Sources

  1. Matthews DR et al. Homeostasis model assessment. Diabetologia, 1985

Cite this calculator

Speedy Calculator. (2026). HOMA-IR Calculator (Insulin Resistance). Speedy Calculator. https://speedycalculator.com/calculators/health/homa-ir/