Oxygenation Index Calculator (OI and OSI)

Quick answer

The oxygenation index calculator measures the severity of hypoxaemic respiratory failure in ventilated patients from FiO₂, mean airway pressure and PaO₂, and gives the oxygen saturation index (OSI) when only SpO₂ is available.

%
cmH₂O
mmHg
%
Oxygenation index
12.9
Moderate (8–16)
Oxygen saturation index
9.8

Unlike the P/F ratio, the oxygenation index accounts for how much ventilator pressure is needed. It is used in neonatal and paediatric intensive care: an OI above 25 is severe and above 40 has been used as a threshold for ECMO.

How to use the Oxygenation Index Calculator

  1. FiO₂
  2. Mean airway pressure
  3. PaO₂
  4. SpO₂

Results update as you type, and every field accepts the units shown in its menu.

How it works

Enter FiO₂, mean airway pressure from the ventilator and PaO₂ (or SpO₂).

Inputs explained

Field What to enter
FiO₂ In %
Mean airway pressure In cmH₂O
PaO₂ In mmHg
SpO₂ In %

What each result means

  • Oxygenation index = [FiO₂]×[Mean airway pressure]÷[PaO₂]
  • Oxygen saturation index = [FiO₂]×[Mean airway pressure]÷[SpO₂]

Example values

How the main result changes when FiO₂ changes and everything else stays at the example values above:

FiO₂ (%) Oxygenation index
30 6.4
45 9.6
60 12.9
75 16.1
90 19.3

Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.

Formula

OI = FiO₂ (%) × mean airway pressure (cmH₂O) ÷ PaO₂ (mmHg) OSI = FiO₂ (%) × mean airway pressure ÷ SpO₂ (%)

Worked example

Inputs — FiO₂: 60 %; Mean airway pressure: 15 cmH₂O; PaO₂: 70 mmHg; SpO₂: 92 %.
Results — Oxygenation index = 12.9; Oxygen saturation index = 9.8.

Key terms

OI
Oxygenation index.
OSI
Oxygen saturation index.

Frequently asked questions

What is a high oxygenation index?

Above 16 in paediatric ARDS (PALICC) is severe; above 40 may prompt ECMO consideration.

Why include mean airway pressure?

It reflects how much ventilatory support is needed to achieve the oxygenation.

When is OSI used?

When arterial blood gases are not available and SpO₂ is 97% or less.

Sources

  1. PALICC – Pediatric acute respiratory distress syndrome consensus recommendations (2023)

Cite this calculator

Speedy Calculator. (2026). Oxygenation Index Calculator (OI and OSI). Speedy Calculator. https://speedycalculator.com/calculators/health/oxygenation-index/