Fatty liver disease affects about a quarter of adults worldwide, but only a minority develop serious scarring. The NAFLD fibrosis score uses routine data to find those who need further tests or specialist care.
How to use the NAFLD Fibrosis Score Calculator
- Age
- Weight
- Height
- Impaired fasting glucose or diabetes
- AST
- ALT
- Platelets
- Albumin
Results update as you type, and every field accepts the units shown in its menu.
How it works
Enter the patient’s details and lab results.
Inputs explained
| Field | What to enter |
|---|---|
| Age | In years |
| Weight | Units: kg, lb, st, g |
| Height | Units: cm, in, m, ft, mm |
| Impaired fasting glucose or diabetes | Choose one: No, Yes |
| AST | In U/L |
| ALT | In U/L |
| Platelets | In ×10⁹/L |
| Albumin | Units: g/dL, g/L |
What each result means
- BMI = [Weight]÷([Height]÷100)^2
- NAFLD fibrosis score = -1.675 + 0.037×[Age] + 0.094×[BMI] + 1.13×[Impaired fasting glucose or diabetes] + 0.99×[AST]÷[ALT] – 0.013×[Platelets] – 0.66×[Albumin]
Example values
How the main result changes when Age changes and everything else stays at the example values above:
| Age (years) | NAFLD fibrosis score |
|---|---|
| 27.5 | -1.12 |
| 41.25 | -0.611 |
| 55 | -0.102 |
| 68.75 | 0.406 |
| 82.5 | 0.915 |
| 110 | 1.933 |
Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.
Formula
NFS = −1.675 + 0.037 × age + 0.094 × BMI + 1.13 × (impaired fasting glucose or diabetes) + 0.99 × AST/ALT − 0.013 × platelets (×10⁹/L) − 0.66 × albumin (g/dL)
< −1.455 low (F0–F2) · −1.455 to 0.676 indeterminate · > 0.676 high (F3–F4)
Worked example
Inputs — Age: 55 years; Weight: 95 kg; Height: 172 cm; Impaired fasting glucose or diabetes: Yes; AST: 45 U/L; ALT: 50 U/L; Platelets: 210 ×10⁹/L; Albumin: 4.2 g/dL.
Results — BMI = 32.1; NAFLD fibrosis score = -0.102; Fibrosis = Indeterminate – consider elastography.
Key terms
- NFS
- NAFLD fibrosis score.
Frequently asked questions
What is MASLD?
Metabolic dysfunction-associated steatotic liver disease, the new name for NAFLD.
What is a good NAFLD fibrosis score?
Below −1.455.
How can fatty liver be reversed?
Losing 7–10% of body weight, exercise and controlling diabetes.