In men, too much testosterone is converted to estradiol by the aromatase enzyme, especially with obesity. A low T/E2 ratio is linked with poor sperm production, and aromatase inhibitors can improve it under specialist care.
How to use the Testosterone to Estradiol Ratio Calculator
- Total testosterone
- Estradiol
Results update as you type, and every field accepts the units shown in its menu.
How it works
Enter morning testosterone and estradiol results from the same blood sample.
Inputs explained
| Field | What to enter |
|---|---|
| Total testosterone | Units: ng/dL, nmol/L |
| Estradiol | Units: pg/mL, pmol/L |
Example values
How the main result changes when Total testosterone changes and everything else stays at the example values above:
| Total testosterone (ng/dL) | Testosterone / estradiol ratio |
|---|---|
| 225 | 7.5 |
| 337.5 | 11.3 |
| 450 | 15 |
| 562.5 | 18.8 |
| 675 | 22.5 |
| 900 | 30 |
Health note: this calculator is for education and screening only and is not a diagnosis or treatment advice. Discuss your results with a qualified clinician.
Formula
T/E2 = testosterone (ng/dL) ÷ estradiol (pg/mL)
Testosterone: 1 nmol/L = 28.84 ng/dL · Estradiol: 1 pg/mL = 3.671 pmol/L
A ratio below 10 is considered abnormal in men
Worked example
Inputs — Total testosterone: 450 ng/dL; Estradiol: 30 pg/mL.
Results — Testosterone / estradiol ratio = 15.
Key terms
- Aromatase
- Enzyme that converts testosterone to estradiol.
Frequently asked questions
What is a normal T/E2 ratio in men?
10 or more when testosterone is in ng/dL and estradiol in pg/mL.
What lowers the ratio?
Obesity, ageing, some medicines and alcohol.
Can it be treated?
Weight loss helps; specialists may use aromatase inhibitors.